Losing Weight Cools Inflammation

At Pill Advised we take a strong interest in fighting inflammation.

 

Inflammation has emerged as a major cause of the leading health problems of our time—obesity, high blood pressure, heart disease, diabetes, cancer and Alzheimer’s.

 

And as we have written, there is a strong connection between nutrition, body weight and inflammation.

 

A fascinating study has found that postmenopausal women who were overweight or obese and lost at least 5 percent of their body weight had a measurable reduction in markers of inflammation.

 

Anne McTiernan, M.D., Ph.D.

“Both obesity and inflammation have been shown to be related to several types of cancer, and this study shows that if you reduce weight, you can reduce inflammation as well,” said Anne McTiernan, M.D., Ph.D., director of the Prevention Center at the Fred Hutchinson Cancer Research Center in Seattle, Wash.

 

Read Dr. Nancy Cotter’s Pain and the Anti-Inflammatory Diet

 

Women in the trial who were assigned to a weight loss intervention had a goal of 10 percent weight reduction during the course of one year achieved through a diet intervention with or without aerobic exercise.

 

“So this program was highly achievable and reproducible. We are not talking about drastic weight loss,” said McTiernan.

 

The researchers measured levels of C-reactive protein, serum amyloid A, interleukin-6, leukocyte and neutrophil in 439 women.

 

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At the end of one year, C-reactive protein reduced by 36.1 percent in the diet-alone group and by 41.7 percent in the diet and exercise group. Interleukin-6 decreased by 23.1 percent in the diet group and 24.3 percent in the diet and exercise group.

 

“This study adds to the growing understanding we have about the link between obesity and cancer, and it appears we can affect inflammation directly through nonpharmaceutical means,” said McTiernan.

 

Learn How Fish Oil Reduces Inflammation

 

Reference:

 

Cancer Res. 2012 May 1;72(9):2314-26. doi: 10.1158/0008-5472.CAN-11-3092. “Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial.” Imayama I, Ulrich CM, Alfano CM, Wang C, Xiao L, Wener MH, Campbell KL, Duggan C, Foster-Schubert KE, Kong A, Mason CE, Wang CY, Blackburn GL, Bain CE, Thompson HJ, McTiernan A. Epidemiology Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington